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Most people who take Topamax (topiramate) have little or no problem with side effects.
Phenytoin is a powerful, effective medication for treating and preventing seizures but it may cause serious side effects and, infrequently, liver damage.
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In some cases we actually are trying to numb the area in and surrounding the eye because the pain is situated there.
However, similarities exist among most of the congenital abnormalities caused by the AEDs (see the Table, below).
It is still one of the most potent in preventing major seizures of tonic-clonic and other types, but its troublesome side effects have meant that the other, newer drugs such as Tegretol and Epilim are usually selected instead.
Interestingly enough, studies have shown that 10-45 percent of people with epilepsy have seizures that occur predominantly or exclusively during sleep or occur with sleep deprivation.
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In addition, the mean two-hour phenytoin level in women in whom eclampsia subsequently developed was higher than the mean level for the phenytoin-treated group as a whole.
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I think we need to be more conservative, particularly because this is a pediatric population.
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Diagnosis also requires a thorough medical history describing seizure characteristics and frequency.
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